White Paper

A Modified Chronic Ocular Hypertension Rat Model for Retinal Ganglion Cell Neuroprotection

This study aimed to modify a chronic ocular hypertension (OHT) rat model to screen for potential compounds to protect retinal ganglion cells (RGCs) from responding to increased intraocular pressure (IOP). The modified OHT model may provide an effective and reliable method for screening drugs to protect RGCs from glaucoma.