Month: March 2021

Cytotoxicity Score Zero

What If…. I Fail Cytotoxicity

Cytotoxicity is a biocompatibility test that every single medical device and material needs to undergo during its development. It is a critical test to ensure that your device or the materials in your device do not cause cell death or inhibit cell growth. So, what happens if your device fails this crucial first test?

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Risk Assessment Formula

Threshold of Toxicological Concern

The Threshold of Toxicological Concern (TTC) is a pragmatic risk assessment tool and is considered to be an exposure level below which the risk of adverse effects to human health is expected to be negligible.  TTC values for a given compound can be derived using its molecular structure to determine the hazard ranking based on the Cramer classification. 

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